Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 7/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682169 | 0.84 | DRD2 (0.49) | DRD2ADRA1A | |
| SCHEMBL12726887 | 0.83 | OPRL1 (0.61) | DRD2ABCB1 | |
| SCHEMBL4684452 | 0.81 | DRD2 (0.56) | CYP2D6CYP3A4DRD2ADRA1AABCB1 | |
| SCHEMBL4687011 | 0.81 | OPRL1 (0.51) | CYP2D6 | |
| SCHEMBL4240927 | 0.79 | NPC1 (0.43) | CYP2D6MAPK1ALDH1A1CYP3A4DRD2 | |
| SCHEMBL7331119 | 0.79 | OPRL1 (0.51) | DRD2ABCB1 | |
| SCHEMBL4688424 | 0.79 | DRD2 (0.46) | ALDH1A1DRD2ADRA1A | |
| SCHEMBL4683031 | 0.77 | OPRL1 (0.75) | CYP2D6DRD2 | |
| SCHEMBL17869355 | 0.76 | TSHR (0.55) | ALDH1A1 | |
| SCHEMBL11894644 | 0.72 | TSHR (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |