Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.48 |
| ▸ | CTSK | P43235 | 9/20 | 0.48 |
| ▸ | EEF2K | O00418 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.41 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147765 | 1.00 | CTSS (0.48) | CTSSCTSKEEF2KKDM4EGAA | |
| SCHEMBL28008559 | 1.00 | CTSS (0.48) | CTSSCTSKEEF2KKDM4EGAA | |
| SCHEMBL16680854 | 0.87 | CTSS (0.43) | CTSSCTSKCTSLCTSB | |
| SCHEMBL16680852 | 0.87 | CTSS (0.43) | CTSSCTSKCTSLCTSB | |
| SCHEMBL14448530 | 0.87 | CTSS (0.47) | CTSSCTSKCTSLCTSBHTT | |
| SCHEMBL321050 | 0.85 | CTSS (0.50) | CTSSCTSKEEF2KEGLN2EGLN1 | |
| SCHEMBL321049 | 0.85 | CTSS (0.50) | CTSSCTSKEEF2KEGLN2EGLN1 | |
| SCHEMBL4968810 | 0.85 | CTSS (0.50) | CTSSCTSKEEF2KEGLN2EGLN1 | |
| SCHEMBL3874575 | 0.84 | CTSS (0.48) | CTSSCTSK | |
| SCHEMBL15654514 | 0.84 | CYP26A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104752-A1 | DIHYDROPYRIDONES AS ELASTASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-09-04 | — | — | WO | disclosed |