SCHEMBL23800751

SCHEMBL23800751

COC[C@@H]1CC[C@H](n2cnc3c(C)ncnc32)O1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.47
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 2/20 0.44
LMNA P02545 1/20 0.44
ALB P02768 1/20 0.44
ADORA3 P0DMS8 1/20 0.41
CYP2C19 P33261 1/20 0.41
TP53 P04637 1/20 0.41
CYP2C9 P11712 1/20 0.41
NFKB1 P19838 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 1/20 0.41
APEX1 P27695 1/20 0.41
PI4KA P42356 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
ADCY1 Q08828 1/20 0.41
PI4K2B Q8TCG2 1/20 0.41
PI4K2A Q9BTU6 1/20 0.41
PI4KB Q9UBF8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20624631 0.87 BCHE (0.57) BCHEALDH1A1MAPK1LMNAALB
SCHEMBL22524135 0.87 BCHE (0.57) BCHEALDH1A1MAPK1LMNAALB
SCHEMBL4745241 0.87 BCHE (0.57) BCHEALDH1A1MAPK1LMNAALB
SCHEMBL23516968 0.87 BCHE (0.57) BCHEALDH1A1MAPK1LMNAALB
SCHEMBL27574575 0.87 BCHE (0.44) BCHEALDH1A1MAPK1LMNAALB
SCHEMBL23344693 0.86 ALDH1A1 (0.46) BCHEALDH1A1MAPK1LMNAALB
SCHEMBL12567150 0.85 BCHE (0.47) BCHEALDH1A1MAPK1LMNAALB
SCHEMBL23254277 0.85 ALDH1A1 (0.60) ALDH1A1MAPK1LMNAALBCYP2C19
SCHEMBL19147079 0.85 ALDH1A1 (0.46) BCHEALDH1A1MAPK1LMNAALB
SCHEMBL12149460 0.85 ALDH1A1 (0.60) ALDH1A1MAPK1LMNAALBCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021178818-A2 THERAPEUTIC AGENTS AND CONJUGATES THEREOF BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) 2021-09-10 WO disclosed