Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.30 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
| ▸ | LYN | P07948 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4490917 | 0.93 | BPTF (0.31) | KDM4ETOP2AFGFR1BPTFCECR2 | |
| SCHEMBL4490928 | 0.92 | KDM4E (0.32) | KDM4ETOP2AFGFR1BPTFCECR2 | |
| SCHEMBL4482238 | 0.89 | LYN (0.32) | LYN | |
| SCHEMBL4489416 | 0.88 | KDM4E (0.32) | KDM4EFGFR1ADORA3BPTFCECR2 | |
| SCHEMBL4745803 | 0.84 | KCNH2 (0.35) | ADORA3 | |
| SCHEMBL4497287 | 0.81 | HTR2A (0.36) | KDM4EFGFR1 | |
| SCHEMBL4489726 | 0.81 | KDM4E (0.30) | KDM4E | |
| SCHEMBL4741763 | 0.81 | KDM4E (0.35) | KDM4ETOP2AFGFR1BPTFCECR2 | |
| SCHEMBL3986451 | 0.81 | JAK2 (0.36) | ADORA3 | |
| SCHEMBL3988447 | 0.81 | KDM4E (0.32) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107398-A2 | PYRAZINE COMPOUNDS | BASF SE (DE) | 2008-09-12 | — | — | WO | disclosed |