Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744316 | 0.91 | PDE2A (0.33) | LYNPDE2APOLBSMN1; SMN2USP1 | |
| SCHEMBL4742187 | 0.85 | USP1 (0.33) | KDM4EUSP1 | |
| SCHEMBL4913222 | 0.85 | PDPK1 (0.32) | — | |
| SCHEMBL4482238 | 0.84 | LYN (0.32) | LYNADORA2AADORA1SRC | |
| SCHEMBL3986102 | 0.81 | USP1 (0.31) | KDM4EUSP1 | |
| SCHEMBL4745295 | 0.81 | KDM4E (0.32) | KDM4ETOP2ABPTFCECR2BRD9 | |
| SCHEMBL4490928 | 0.80 | KDM4E (0.32) | KDM4ETOP2ABPTFCECR2BRD9 | |
| SCHEMBL4489726 | 0.78 | KDM4E (0.30) | KDM4ESMN1; SMN2 | |
| SCHEMBL4485590 | 0.77 | TP53 (0.33) | POLBSMN1; SMN2 | |
| SCHEMBL3993899 | 0.77 | TP53 (0.33) | POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107398-A2 | PYRAZINE COMPOUNDS | BASF SE (DE) | 2008-09-12 | — | — | WO | disclosed |