Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805417 | 0.92 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9787289 | 0.90 | SMN1; SMN2 (0.74) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3264835 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL26981901 | 0.84 | KDM4E (0.63) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7642387 | 0.83 | HRH3 (0.56) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL17334551 | 0.83 | HRH3 (0.56) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL8467184 | 0.83 | HRH3 (0.56) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL11050244 | 0.81 | HRH3 (0.54) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL3267040 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8672714 | 0.81 | SMN1; SMN2 (0.71) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |