Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 16/20 | 0.62 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939737 | 0.97 | CXCR4 (0.66) | CXCR4CXCL12KDM4EHRH4HRH3 | |
| SCHEMBL3695429 | 0.95 | CXCR4 (0.57) | CXCR4CXCL12KDM4EALDH1A1HRH4 | |
| SCHEMBL5932743 | 0.92 | CXCR4 (0.60) | CXCR4CXCL12ALDH1A1HRH4HRH3 | |
| SCHEMBL11523136 | 0.92 | CXCR4 (0.57) | CXCR4CXCL12KDM4EALDH1A1HRH4 | |
| SCHEMBL9417435 | 0.89 | CXCR4 (0.61) | CXCR4CXCL12KDM4EALDH1A1HRH4 | |
| SCHEMBL17733777 | 0.89 | CXCR4 (0.61) | CXCR4CXCL12KDM4EALDH1A1HRH4 | |
| SCHEMBL16506040 | 0.87 | CXCR4 (0.56) | CXCR4CXCL12 | |
| SCHEMBL11453275 | 0.87 | CXCR4 (0.56) | CXCR4CXCL12KDM4E | |
| SCHEMBL11324082 | 0.87 | CXCR4 (0.56) | CXCR4CXCL12 | |
| SCHEMBL10935703 | 0.87 | CXCR4 (0.56) | CXCR4CXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112636-A1 | CHAIN EXTENDERS | ALBEMARLE CORPORATION (US) | 2008-09-18 | — | — | WO | disclosed |