SCHEMBL4745530

SCHEMBL4745530

CC(C)NCCCCCCN(CCCCCCN)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.39
PAOX Q6QHF9 2/20 0.33
CA12 O43570 1/20 0.32
F13A1 P00488 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CYP1A2 P05177 1/20 0.32
CA3 P07451 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
THPO P40225 1/20 0.32
MTOR P42345 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19542960 0.90 HRH4 (0.36) HRH4HRH3
SCHEMBL19542940 0.88 HRH4 (0.34) HRH4HRH3
SCHEMBL19546064 0.86 HRH4 (0.33) HRH4HRH3
SCHEMBL20118898 0.85 TDP1 (0.32) CYP2C9TDP1
SCHEMBL9739467 0.85 TDP1 (0.32) CYP2C9TDP1
SCHEMBL20438332 0.84 HRH4 (0.33) HRH4HRH3
SCHEMBL20445498 0.84 HRH4 (0.31) HRH4HRH3
SCHEMBL20968106 0.84 CA12 (0.43) PAOXCA12F13A1CA1CA2
SCHEMBL20968105 0.84 CA12 (0.43) PAOXCA12F13A1CA1CA2
SCHEMBL20968107 0.84 CA12 (0.43) PAOXCA12F13A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008130721-A1 PREPARATION OF SECONDARY DIAMINES ALBEMARLE CORPORATION (US) 2008-10-30 WO disclosed
WO-2008112636-A1 CHAIN EXTENDERS ALBEMARLE CORPORATION (US) 2008-09-18 WO disclosed