Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746157 | 0.88 | TRPV4 (0.30) | — | |
| SCHEMBL20445498 | 0.87 | HRH4 (0.31) | — | |
| SCHEMBL19546064 | 0.85 | HRH4 (0.33) | — | |
| SCHEMBL20445573 | 0.85 | TRPV4 (0.31) | — | |
| SCHEMBL4745530 | 0.85 | CHRM2 (0.39) | TDP1CYP2C9 | |
| SCHEMBL9739467 | 0.84 | TDP1 (0.32) | TDP1CYP2C9CYP2C19 | |
| SCHEMBL19542940 | 0.83 | HRH4 (0.34) | — | |
| SCHEMBL10617941 | 0.82 | MEN1 (0.32) | — | |
| SCHEMBL19542960 | 0.81 | HRH4 (0.36) | — | |
| SCHEMBL4917625 | 0.81 | CYP2C9 (0.36) | TDP1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | disclosed |