SCHEMBL4745532

SCHEMBL4745532

COC1CCCC(OC=O)C1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.36
DPP7 Q9UHL4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5355629 0.91
SCHEMBL5482843 0.81 DPP4 (0.40) DPP4DPP7
SCHEMBL14270060 0.81 DPP4 (0.40) DPP4DPP7
SCHEMBL633120 0.78 MCHR1 (0.32)
SCHEMBL12438852 0.78 MCHR1 (0.32)
SCHEMBL12166897 0.78 MCHR1 (0.32)
SCHEMBL13447535 0.78 HPGD (0.31)
SCHEMBL11210270 0.78 ADH1A (0.35)
SCHEMBL96545 0.78
Formic Acid Methyl Ester SCHEMBL28144366 0.77 DPP4 (0.33) DPP4DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008119715-A1 1- (1-CYCLOHEXYL-4-PIPERIDINYL) -1, 3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES WHICH HAVE ACTIVITY ON THE M1 RECEPTOR AND THEIR USE IN MEDICINE GLAXO GROUP LIMITED (GB) 2008-10-09 WO disclosed