Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745762 | 1.00 | DPP4 (0.33) | DPP4DPP8DPP9DPP7HRH3 | |
| SCHEMBL4745761 | 1.00 | DPP4 (0.33) | DPP4DPP8DPP9DPP7HRH3 | |
| SCHEMBL2282417 | 0.89 | CHRM2 (0.33) | — | |
| SCHEMBL2277732 | 0.89 | CHRM2 (0.33) | — | |
| SCHEMBL4748600 | 0.85 | GPR119 (0.32) | DPP4DPP8DPP9DPP7HRH3 | |
| SCHEMBL4748594 | 0.85 | GPR119 (0.32) | DPP4DPP8DPP9DPP7HRH3 | |
| SCHEMBL4748591 | 0.85 | GPR119 (0.32) | DPP4DPP8DPP9DPP7HRH3 | |
| SCHEMBL4786529 | 0.85 | CHRM2 (0.34) | DPP4DPP8DPP9DPP7HRH3 | |
| SCHEMBL4786542 | 0.85 | CHRM2 (0.34) | DPP4DPP8DPP9DPP7HRH3 | |
| SCHEMBL4786536 | 0.85 | CHRM2 (0.34) | DPP4DPP8DPP9DPP7HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119715-A1 | 1- (1-CYCLOHEXYL-4-PIPERIDINYL) -1, 3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES WHICH HAVE ACTIVITY ON THE M1 RECEPTOR AND THEIR USE IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119715-A1 | 1- (1-CYCLOHEXYL-4-PIPERIDINYL) -1, 3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES WHICH HAVE ACTIVITY ON THE M1 RECEPTOR AND THEIR USE IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |