Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626635 | 0.87 | MAOA (0.44) | MAOAMAOBCYP11B2PTGS2CYP11B1 | |
| Hydrochloric Acid SCHEMBL30361381 | 0.85 | MAOA (0.42) | MAOAMAOBCYP11B2PTGS2CYP11B1 | |
| Hydrochloric Acid SCHEMBL4604224 | 0.85 | MAOA (0.42) | MAOAMAOBCYP11B2PTGS2CYP11B1 | |
| Hydrochloric Acid SCHEMBL4604472 | 0.85 | MAOA (0.42) | MAOAMAOBCYP11B2PTGS2CYP11B1 | |
| SCHEMBL28321113 | 0.85 | MAOA (0.42) | MAOAMAOBCYP11B2PTGS2CYP11B1 | |
| Trifluoroacetic Acid SCHEMBL3948941 | 0.78 | MAOA (0.47) | MAOAMAOBMTNR1AMTNR1BKDM1A | |
| Formic Acid SCHEMBL8436468 | 0.73 | CYP1A2 (0.52) | MAOAMAOBCYP1A2HTR2ADRD3 | |
| SCHEMBL2302098 | 0.71 | MAOA (0.43) | MAOAMAOBMTNR1AMTNR1BCYP11B2 | |
| Formic Acid SCHEMBL5378796 | 0.71 | CYP1A2 (0.50) | MAOAMAOBCYP1A2HTR2ADRD3 | |
| SCHEMBL4623181 | 0.70 | KDM1A (0.50) | MAOBCYP11B2PTGS2CYP11B1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113795-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-09-25 | — | — | WO | disclosed |