Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14658803 | 0.94 | KDM4E (0.49) | CYP2D6KDM4EALDH1A1CYP1A2MAPK1 | |
| SCHEMBL14658573 | 0.90 | KDM4E (0.46) | CYP2D6KDM4EALDH1A1CYP1A2MAPK1 | |
| SCHEMBL3978680 | 0.85 | KDM4E (0.52) | CYP2D6KDM4EALDH1A1CYP1A2MAPK1 | |
| SCHEMBL3372372 | 0.84 | KDM4E (0.49) | CYP2D6KDM4EALDH1A1CYP1A2MAPK1 | |
| SCHEMBL19291714 | 0.84 | TAAR1 (0.54) | CYP2D6KDM4EALDH1A1CYP1A2MAPK1 | |
| SCHEMBL8418971 | 0.84 | KCNA3 (0.53) | PPARGPPARA | |
| SCHEMBL27825974 | 0.84 | KDM4E (0.48) | CYP2D6KDM4EALDH1A1CYP1A2MAPK1 | |
| SCHEMBL8499307 | 0.83 | PPARA (0.58) | CYP2D6PPARGPPARA | |
| SCHEMBL4568869 | 0.83 | CYP2D6 (0.57) | CYP2D6KDM4EALDH1A1CYP1A2MAPK1 | |
| SCHEMBL10235898 | 0.83 | CYP2D6 (0.54) | CYP2D6KDM4EALDH1A1CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |