Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062788 | 0.91 | KDM4E (0.50) | KDM4EALDH1A1CYP2D6CYP1A2MAPK1 | |
| SCHEMBL31214329 | 0.91 | KDM4E (0.50) | KDM4EALDH1A1CYP2D6CYP1A2MAPK1 | |
| SCHEMBL7254138 | 0.85 | PRSS1 (0.47) | KDM4EALDH1A1MAPK1GGPS1MAOB | |
| SCHEMBL4745845 | 0.85 | CYP2D6 (0.50) | KDM4EALDH1A1CYP2D6CYP1A2MAPK1 | |
| SCHEMBL13672772 | 0.85 | MAOB (0.46) | KDM4EALDH1A1MAPK1BCHEMAOB | |
| SCHEMBL10272584 | 0.84 | KDM4E (0.70) | KDM4EALDH1A1CYP2D6CYP1A2MAPK1 | |
| SCHEMBL13541357 | 0.84 | TSHR (0.51) | CYP2D6GGPS1 | |
| SCHEMBL31361961 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1CYP2D6CYP1A2MAPK1 | |
| SCHEMBL6044078 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1CYP2D6CYP1A2MAPK1 | |
| SCHEMBL31361968 | 0.83 | ALDH1A1 (0.52) | KDM4EALDH1A1CYP2D6CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053277-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2009-04-30 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |