Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.38 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | FLT4 | P35916 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 6/20 | 0.37 |
| ▸ | ABL1 | P00519 | 5/20 | 0.37 |
| ▸ | KIT | P10721 | 5/20 | 0.37 |
| ▸ | RAF1 | P04049 | 4/20 | 0.37 |
| ▸ | ARAF | P10398 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | BLK | P51451 | 1/20 | 0.36 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686817 | 0.96 | KDR (0.40) | KDRFLT1FLT4BRAFABL1 | |
| SCHEMBL4238135 | 0.91 | SMN1; SMN2 (0.41) | KDRFLT1FLT4MCHR1FGFR1 | |
| SCHEMBL4233858 | 0.89 | SMN1; SMN2 (0.42) | KDRBRAFABL1KITRAF1 | |
| SCHEMBL4242226 | 0.88 | SMN1; SMN2 (0.43) | KDRFLT1FLT4MCHR1FGFR1 | |
| SCHEMBL4229188 | 0.88 | MCHR1 (0.40) | KDRFLT1FLT4MCHR1 | |
| SCHEMBL4236281 | 0.87 | TAS1R3 (0.45) | MCHR1 | |
| SCHEMBL4233470 | 0.86 | MCHR1 (0.40) | KDRFLT1FLT4MCHR1 | |
| SCHEMBL4233219 | 0.86 | SMN1; SMN2 (0.44) | MCHR1 | |
| SCHEMBL4799376 | 0.86 | ERBB2 (0.35) | KDRFLT1FLT4MCHR1FGFR1 | |
| SCHEMBL4240643 | 0.86 | PDE4D (0.42) | KDRFLT1FLT4MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |