Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14042631 | 0.82 | CYP1A2 (0.46) | HTR2AMEN1KMT2ATAAR1CYP1A2 | |
| SCHEMBL23243766 | 0.82 | ATM (0.54) | MEN1KMT2AIDO1TAAR1CYP2D6 | |
| SCHEMBL29445352 | 0.82 | ATM (0.54) | MEN1KMT2AIDO1TAAR1CYP2D6 | |
| SCHEMBL23243765 | 0.82 | ATM (0.54) | MEN1KMT2AIDO1TAAR1CYP2D6 | |
| SCHEMBL31545209 | 0.79 | HTR2A (1.00) | HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL1740902 | 0.79 | HTR2A (1.00) | HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL1740903 | 0.79 | HTR2A (1.00) | HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL3460220 | 0.79 | HTR2A (1.00) | HTR2AIDO1ADRA1ATAAR1 | |
| Hydrochloric Acid SCHEMBL29542459 | 0.78 | HTR2A (0.97) | HTR2AIDO1ADRA1ATAAR1 | |
| Hydrochloric Acid SCHEMBL3486527 | 0.78 | HTR2A (0.97) | HTR2AIDO1ADRA1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123821-A1 | 4, 5-DIHYDRO-LH-IMIDAZOL-2-AMINE DERIVATIVES FOR USE IN THE TREATMENT OF RESPIRATORY, CARDIOVASCULAR, NEUROLOGICAL OR GASTROINTESTINAL DISORDERS | ALBIREO AB (SE) | 2008-10-16 | — | — | WO | claimed |
| WO-2008123821-A1 | 4, 5-DIHYDRO-LH-IMIDAZOL-2-AMINE DERIVATIVES FOR USE IN THE TREATMENT OF RESPIRATORY, CARDIOVASCULAR, NEUROLOGICAL OR GASTROINTESTINAL DISORDERS | ALBIREO AB (SE) | 2008-10-16 | — | — | WO | disclosed |