Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23243766 | 1.00 | ATM (0.54) | ATML3MBTL1MEN1KMT2ACYP2D6 | |
| SCHEMBL29445352 | 1.00 | ATM (0.54) | ATML3MBTL1MEN1KMT2ACYP2D6 | |
| SCHEMBL4748467 | 0.87 | ABCB1 (0.47) | ATML3MBTL1MEN1KMT2ASCN4A | |
| Hydrochloric Acid SCHEMBL4750300 | 0.85 | ABCB1 (0.46) | ATML3MBTL1MEN1KMT2AIDO1 | |
| SCHEMBL12706123 | 0.84 | IDO1 (0.52) | ATML3MBTL1MEN1KMT2ACYP2D6 | |
| SCHEMBL14042175 | 0.83 | ATM (0.42) | ATML3MBTL1MEN1KMT2ACYP2D6 | |
| SCHEMBL4745939 | 0.82 | HTR2A (0.65) | MEN1KMT2ACYP2D6IDO1TAAR1 | |
| SCHEMBL9638844 | 0.81 | IDO1 (0.57) | ATML3MBTL1MEN1KMT2ACYP2D6 | |
| SCHEMBL30249073 | 0.79 | KMT2A (0.64) | KMT2AIDO1TAAR1 | |
| SCHEMBL14655700 | 0.79 | KMT2A (0.64) | KMT2AIDO1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210114977-A1 | AN IMPROVED ASYMMETRIC SYNTHESIS OF alpha-BRANCHED CHIRAL AMINES | Piramal Enterprises Limited (IN) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210114977-A1 | AN IMPROVED ASYMMETRIC SYNTHESIS OF alpha-BRANCHED CHIRAL AMINES | SLC6A12, BCAT2, BET1 | ATM 1052/4885L3MBTL1 1601/4885MEN1 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.