Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.60 |
| ▸ | GNA15 | P30679 | 1/20 | 0.58 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14043994 | 0.91 | FFAR1 (0.65) | FFAR1GNA15PTGER3FFAR4TDP1 | |
| SCHEMBL4748821 | 0.90 | FFAR1 (0.74) | FFAR1GNA15PTGER3FFAR4TDP1 | |
| SCHEMBL11248670 | 0.88 | HIF1A (0.58) | RXRARXRBRXRGADRB3 | |
| SCHEMBL14044092 | 0.88 | FFAR1 (0.60) | FFAR1GNA15PTGER3FFAR4TDP1 | |
| SCHEMBL14044103 | 0.85 | HIF1A (0.66) | FFAR1GNA15PTGER3FFAR4TDP1 | |
| SCHEMBL14044096 | 0.85 | FFAR1 (0.60) | FFAR1GNA15PTGER3FFAR4TDP1 | |
| SCHEMBL14043645 | 0.84 | FFAR1 (0.57) | FFAR1GNA15PTGER3FFAR4TDP1 | |
| SCHEMBL14044095 | 0.84 | FFAR1 (0.65) | FFAR1GNA15PTGER3FFAR4TDP1 | |
| SCHEMBL14043908 | 0.84 | FFAR1 (0.65) | FFAR1GNA15PTGER3FFAR4TDP1 | |
| SCHEMBL14044105 | 0.82 | MAPK14 (0.58) | FFAR1GNA15PTGER3FFAR4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121570-A1 | COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2008-10-09 | — | — | WO | disclosed |