Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.41 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.41 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | STK32B | Q9NY57 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.41 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 2/20 | 0.39 |
| ▸ | ATRIP | Q8WXE1 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746017 | 0.89 | POLB (0.49) | TYK2DYRK1AATRATRIPNPC1 | |
| SCHEMBL13320340 | 0.87 | PDGFRB (0.51) | PDGFRBPDGFRACYP2A6HSP90AA1BIRC5 | |
| SCHEMBL4746252 | 0.85 | ALDH1A1 (0.41) | TOP2ANPC1POLBRAB9AALDH1A1 | |
| SCHEMBL4745816 | 0.84 | HTR2B (0.40) | PIM1TOP2ANPC1RAB9AALDH1A1 | |
| SCHEMBL4746386 | 0.83 | ALDH1A1 (0.38) | TOP2AALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL4746287 | 0.83 | PTPRC (0.39) | TOP2AALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL4746335 | 0.83 | ALDH1A1 (0.39) | TOP2APIK3CDALDH1A1HPGDTSHR | |
| SCHEMBL13320390 | 0.82 | ALDH1A1 (0.45) | TOP2AALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL4746241 | 0.82 | ALDH1A1 (0.42) | TOP2AALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL4746384 | 0.82 | ALDH1A1 (0.37) | TOP2APIK3CDPIK3CBPIK3CGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173275-B2 | Azaindenochrysene derivative and organic light-emitting device | CANON KABUSHIKI KAISHA (JP) | 2012-05-08 | — | — | US | disclosed |
| US-8173275-B2 | Azaindenochrysene derivative and organic light-emitting device | CANON KABUSHIKI KAISHA (JP) | 2012-05-08 | — | — | US | disclosed |
| US-20100117526-A1 | NOVEL AZAINDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2010-05-13 | — | — | US | disclosed |
| US-20100117526-A1 | NOVEL AZAINDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100117526-A1 | NOVEL AZAINDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE | NR2E3, OR51E2, AZI2 | PDGFRB 2429/4885PDGFRA 1770/4885CYP2A6 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.