Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 3/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 3/20 | 0.35 |
| ▸ | DHCR7 | Q9UBM7 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4821971 | 0.72 | F2 (0.43) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL10050619 | 0.70 | L3MBTL1 (0.55) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL23832438 | 0.68 | F2 (0.47) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL27271507 | 0.67 | CA1 (0.45) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7374081 | 0.67 | SLC1A3 (0.45) | F2PRSS1PRSS2PRSS3CA1 | |
| Hydroxyamine SCHEMBL259333 | 0.66 | CA1 (0.54) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL23788 | 0.65 | CA1 (0.58) | F2PRSS1PRSS2PRSS3CA1 | |
| Ammonia Solution, Strong SCHEMBL5999943 | 0.65 | CA1 (0.58) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7930818 | 0.65 | CA1 (0.58) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL10846507 | 0.65 | CA1 (0.58) | F2PRSS1PRSS2PRSS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112251-A1 | CYCLOPROPYL-CONTAINING POLYAMINE ANALOGS AS DISEASE THERAPIES | PROGEN PHARMACEUTICALS, INC. (US) | 2008-09-18 | — | — | WO | disclosed |