SCHEMBL4746152

SCHEMBL4746152

CC(N(CCNCCN)C(C)C(C)(C)C)C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.48
CYP2C9 P11712 2/20 0.48
CA12 O43570 5/20 0.40
CA6 P23280 5/20 0.40
CA7 P43166 5/20 0.40
CA9 Q16790 5/20 0.40
CA14 Q9ULX7 5/20 0.40
CA5B Q9Y2D0 5/20 0.40
MEN1 O00255 2/20 0.40
RECQL P46063 2/20 0.40
KMT2A Q03164 2/20 0.40
CA2 P00918 4/20 0.39
CA4 P22748 4/20 0.39
CA5A P35218 4/20 0.39
TDP1 Q9NUW8 3/20 0.39
CA3 P07451 3/20 0.39
ALOX15 P16050 3/20 0.39
LMNA P02545 2/20 0.39
CA1 P00915 2/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4124680 0.79 CYP2C19 (0.56) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL27892766 0.77 CYP2C19 (0.54) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL1263734 0.75 CYP2C19 (0.52) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL19458012 0.75 CHRM2 (0.44) CA12CA6CA7CA9CA14
SCHEMBL9577224 0.73 CYP2C19 (0.50) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL18797279 0.72 CYP2C19 (0.48) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL20612742 0.71 CA12 (0.46) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL3693736 0.71 CYP2C19 (0.47) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL10108999 0.70 CYP2C19 (0.56) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL8766711 0.69 CYP2C19 (0.50) CYP2C19CYP2C9CA12CA6CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008112636-A1 CHAIN EXTENDERS ALBEMARLE CORPORATION (US) 2008-09-18 WO disclosed