Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743106 | 0.80 | MAPK1 (0.58) | MAPK1SRD5A2CNR1CNR2LMNA | |
| SCHEMBL4746218 | 0.80 | MAPK1 (0.63) | MAPK1SRD5A2CNR1CNR2LMNA | |
| SCHEMBL30396659 | 0.80 | MAPK1 (0.63) | MAPK1SRD5A2CNR1CNR2LMNA | |
| SCHEMBL4743101 | 0.79 | HPGD (0.64) | CNR1LMNACDK2MAPTHPGD | |
| SCHEMBL26231411 | 0.78 | MAPK1 (0.46) | MAPK1SRD5A2CNR1CNR2LMNA | |
| SCHEMBL3446105 | 0.77 | SRD5A2 (0.58) | MAPK1SRD5A2CNR1CNR2LMNA | |
| SCHEMBL26231301 | 0.75 | HPGD (0.46) | MAPK1SRD5A2LMNAHTTCES2 | |
| Hydroquinone SCHEMBL9777901 | 0.74 | MAPK1 (1.00) | MAPK1SRD5A2CNR1CNR2LMNA | |
| Hydroquinone SCHEMBL10635396 | 0.74 | MAPK1 (1.00) | MAPK1SRD5A2CNR1CNR2LMNA | |
| SCHEMBL333466 | 0.74 | MAPK1 (1.00) | MAPK1SRD5A2CNR1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |