Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746727 | 0.83 | HPGD (0.68) | HPGDPOLBMAPTRAB9APTGS2 | |
| SCHEMBL4479518 | 0.83 | POLB (0.67) | HPGDPOLBMAPTRAB9AMAOB | |
| SCHEMBL4746236 | 0.79 | MAPK1 (0.59) | HPGDMAPTRAB9APTGS2CDK2 | |
| SCHEMBL38661406 | 0.79 | CYP2D6 (0.54) | HPGDMAPTRAB9AKMT2AMEN1 | |
| SCHEMBL2466074 | 0.78 | HPGD (1.00) | HPGDPOLBMAPTRAB9APTGS2 | |
| SCHEMBL28061936 | 0.78 | MAPT (0.70) | HPGDPOLBMAPTRAB9APTGS2 | |
| SCHEMBL8132899 | 0.76 | MKNK2 (0.52) | HPGDPOLBMAPTRAB9AMAOB | |
| SCHEMBL8481431 | 0.76 | ALDH1A1 (0.56) | MAPTRAB9AMAOAKMT2ALMNA | |
| SCHEMBL8481123 | 0.75 | CA1 (0.53) | MAPTRAB9AMAOAKMT2AMEN1 | |
| SCHEMBL8480798 | 0.75 | CA1 (0.53) | HPGDPOLBMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |