Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 5/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 1/20 | 0.35 |
| ▸ | ATP4B | P51164 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479461 | 0.89 | LSS (0.66) | LSSALDH2MAOAMAOBALDH1A1 | |
| SCHEMBL5039824 | 0.88 | LSS (0.64) | LSSALDH2MAOAMAOBALDH1A1 | |
| SCHEMBL5045728 | 0.86 | LSS (0.52) | LSSALDH2MAOAMAOBALDH1A1 | |
| SCHEMBL5035264 | 0.84 | LSS (0.62) | LSSALDH2MAOAMAOBALDH1A1 | |
| SCHEMBL5038373 | 0.82 | LSS (0.50) | LSSALDH2MAOAMAOBALDH1A1 | |
| SCHEMBL4744399 | 0.76 | MIF (0.48) | LSSMAPT | |
| SCHEMBL4746424 | 0.76 | ALDH2 (0.65) | LSSALDH2MAOAMAOB | |
| SCHEMBL4746357 | 0.76 | ALDH2 (0.65) | LSSALDH2MAOAMAOB | |
| SCHEMBL5040185 | 0.76 | LSS (0.57) | LSSALDH2MAOAMAOBMAPT | |
| SCHEMBL5038961 | 0.75 | LSS (0.70) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107321-A1 | HETEROCYCLIC COMPOUNDS USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |