Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 11/20 | 0.66 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5039824 | 0.99 | LSS (0.64) | LSSALDH2MAOAMAOBALDH1A1 | |
| SCHEMBL5035264 | 0.95 | LSS (0.62) | LSSALDH2MAOAMAOBALDH1A1 | |
| SCHEMBL4746406 | 0.89 | LSS (0.53) | LSSALDH2MAOAMAOBALDH1A1 | |
| SCHEMBL5045728 | 0.88 | LSS (0.52) | LSSALDH2MAOAMAOBALDH1A1 | |
| SCHEMBL5038961 | 0.86 | LSS (0.70) | LSS | |
| Hydrochloric Acid SCHEMBL5038859 | 0.85 | LSS (0.68) | LSS | |
| SCHEMBL5043205 | 0.85 | LSS (0.66) | LSS | |
| SCHEMBL5038302 | 0.84 | LSS (0.74) | LSSALDH1A1MAPT | |
| SCHEMBL5038373 | 0.84 | LSS (0.50) | LSSALDH2MAOAMAOBALDH1A1 | |
| SCHEMBL5035597 | 0.83 | LSS (0.61) | LSSALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0778271-A2 | Aminoalkyl-substituted benzo-heterocyclic compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |