Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.55 |
| ▸ | PPARG | P37231 | 19/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744642 | 0.91 | PPARG (0.55) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL4744013 | 0.90 | PPARA (0.54) | PPARAPPARG | |
| SCHEMBL4748098 | 0.86 | PPARA (0.52) | PPARAPPARG | |
| SCHEMBL4744868 | 0.86 | PPARA (0.51) | PPARAPPARG | |
| SCHEMBL4393111 | 0.81 | PPARG (0.66) | PPARAPPARGCYP2C9KCNH2CYP3A4 | |
| SCHEMBL4748548 | 0.81 | PPARG (0.55) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL4743666 | 0.80 | KDR (0.60) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL4748240 | 0.80 | PPARG (0.59) | PPARAPPARGCYP2C9KCNH2CYP3A4 | |
| SCHEMBL4744629 | 0.80 | KDR (0.62) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL4398734 | 0.80 | PPARG (0.59) | PPARAPPARGCYP2C9KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |