Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408296 | 0.92 | SLC6A4 (0.57) | SLC6A4L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL30808273 | 0.92 | SLC6A4 (0.57) | SLC6A4L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL20745053 | 0.88 | SLC6A4 (0.53) | SLC6A4KDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL2499099 | 0.85 | SLC6A4 (0.45) | SLC6A4KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3081718 | 0.85 | SLC6A4 (0.50) | SLC6A4KDM4EUSP2L3MBTL1ALDH1A1 | |
| SCHEMBL23673569 | 0.83 | SLC6A4 (0.42) | SLC6A4KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL29887121 | 0.83 | SLC6A4 (0.42) | SLC6A4KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL8773585 | 0.83 | SLC6A4 (0.46) | SLC6A4KDM4EUSP2L3MBTL1ALDH1A1 | |
| SCHEMBL2810242 | 0.82 | REN (0.48) | KDM4EL3MBTL1MAPTHPGDNPC1 | |
| SCHEMBL7952850 | 0.82 | CYP3A4 (0.44) | ALDH1A1TDP1LMNAMAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024772-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-03-04 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |