Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746727 | 0.79 | HPGD (0.68) | POLBHPGDMAPTCNR1RAB9A | |
| SCHEMBL3233109 | 0.79 | ERN1 (0.47) | HPGDMAPTTTRKDM4ERORC | |
| SCHEMBL3028435 | 0.79 | KDM4E (0.47) | HPGDMAPTTTRKDM4ERORC | |
| Hydrochloric Acid SCHEMBL10398546 | 0.77 | KDM4E (0.46) | HPGDMAPTTTRKDM4ERORC | |
| SCHEMBL17351004 | 0.77 | KDM4E (0.42) | POLBHPGDMAPTTTRKDM4E | |
| SCHEMBL17063602 | 0.77 | GAA (0.47) | HPGDMAPTKDM4ELMNACYP3A4 | |
| SCHEMBL29772213 | 0.76 | CYP1A2 (0.79) | POLBHPGDMAPTCNR1TTR | |
| SCHEMBL6839373 | 0.76 | CYP1A2 (0.79) | POLBHPGDMAPTCNR1TTR | |
| SCHEMBL4745371 | 0.75 | CNR1 (0.54) | HPGDCNR1CYP3A4TSHRALOX15 | |
| SCHEMBL31443266 | 0.75 | CNR1 (0.67) | POLBHPGDMAPTCNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |