Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | CNR2 | P34972 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SPR | P35270 | 3/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212801 | 0.87 | CNR2 (0.56) | CNR1CNR2SPRALDH1A1TDP1 | |
| SCHEMBL30396659 | 0.80 | MAPK1 (0.63) | CNR1CNR2MAPK1SRD5A2CES2 | |
| SCHEMBL4746218 | 0.80 | MAPK1 (0.63) | CNR1CNR2MAPK1SRD5A2CES2 | |
| SCHEMBL9712397 | 0.77 | SRD5A2 (0.44) | CNR1CNR2MAPK1SRD5A2CES2 | |
| SCHEMBL5355330 | 0.75 | SPR (0.55) | SPRTSHRHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL4746671 | 0.75 | POLB (0.55) | CNR1SRD5A2TSHRALOX15CYP3A4 | |
| SCHEMBL7264321 | 0.74 | CES2 (0.53) | CNR1CNR2MAPK1SRD5A2CES2 | |
| SCHEMBL9779306 | 0.74 | SRD5A2 (0.56) | CNR1CNR2MAPK1SRD5A2CES2 | |
| SCHEMBL1460161 | 0.74 | SRD5A2 (0.50) | CNR1CNR2MAPK1SRD5A2CES2 | |
| SCHEMBL11504324 | 0.74 | ALDH1A1 (0.54) | CNR1CNR2SRD5A2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |