Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL601625 | 0.84 | KMT2A (0.33) | LMNAMAPK1 | |
| SCHEMBL601379 | 0.83 | LMNA (0.33) | POLBLMNAMAPK1 | |
| SCHEMBL3017741 | 0.82 | MEN1 (0.36) | — | |
| SCHEMBL13130604 | 0.81 | SMN1; SMN2 (0.35) | EPHX2LMNAMAPK1 | |
| SCHEMBL19339296 | 0.78 | POLB (0.32) | POLBLMNAMAPK1 | |
| SCHEMBL27888454 | 0.77 | EPHX2 (0.46) | EPHX2 | |
| SCHEMBL30934747 | 0.77 | — | — | |
| SCHEMBL19339360 | 0.76 | EPHX2 (0.33) | EPHX2POLBLMNAMAPK1 | |
| SCHEMBL19339212 | 0.75 | MAPK1 (0.34) | POLBLMNAMAPK1 | |
| SCHEMBL17468555 | 0.75 | MAPK1 (0.34) | POLBLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119721-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119721-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |