Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | GAA | P10253 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 4/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | MC4R | P32245 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CLK1 | P49759 | 1/20 | 0.59 |
| ▸ | GSK3A | P49840 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750544 | 0.90 | MAPT (0.68) | MAPTSMN1; SMN2GAATP53PAX8 | |
| SCHEMBL5332873 | 0.86 | PAX8 (0.85) | MAPTSMN1; SMN2GAATP53PAX8 | |
| SCHEMBL4749735 | 0.86 | PAX8 (0.81) | MAPTSMN1; SMN2GAATP53PAX8 | |
| SCHEMBL3656790 | 0.84 | PAX8 (0.69) | MAPTSMN1; SMN2GAATP53PAX8 | |
| SCHEMBL4747116 | 0.83 | PAX8 (0.67) | MAPTSMN1; SMN2GAATP53PAX8 | |
| SCHEMBL4749024 | 0.83 | PAX8 (0.67) | MAPTSMN1; SMN2GAATP53PAX8 | |
| SCHEMBL4746796 | 0.82 | PAX8 (0.64) | MAPTSMN1; SMN2GAATP53PAX8 | |
| SCHEMBL4749734 | 0.81 | PAX8 (0.67) | MAPTSMN1; SMN2GAATP53PAX8 | |
| SCHEMBL4750019 | 0.81 | PAX8 (0.65) | MAPTSMN1; SMN2GAATP53PAX8 | |
| SCHEMBL4750541 | 0.81 | PAX8 (0.65) | MAPTSMN1; SMN2GAATP53PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119771-A2 | QUINOLINE-S-CARBOXYLIC ACID DERIVATIVES AS TYROSINE KINASE INHIBITORS | CLANOTECH AB (SE) | 2008-10-09 | — | — | WO | disclosed |