Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 8/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030228 | 0.88 | ITGB1 (0.49) | ITGB1ITGAVABL1CTSBCTSS | |
| SCHEMBL3318595 | 0.80 | ITGB1 (0.71) | ITGB1ITGAVCTSBCTSSCTSK | |
| SCHEMBL4626858 | 0.80 | ITGB1 (0.71) | ITGB1ITGAVCTSBCTSSCTSK | |
| SCHEMBL3315439 | 0.80 | ITGB1 (0.71) | ITGB1ITGAVCTSBCTSSCTSK | |
| SCHEMBL4747262 | 0.78 | ITGB1 (0.58) | ITGB1ITGAVCTSBCTSSCTSK | |
| SCHEMBL4750015 | 0.77 | ITGB1 (0.53) | ITGB1ITGAVABL1 | |
| SCHEMBL4626504 | 0.77 | ITGB1 (0.53) | ITGB1ITGAVABL1 | |
| SCHEMBL1030225 | 0.77 | ITGB1 (0.59) | ITGB1ITGAVCTSBCTSSCTSK | |
| SCHEMBL3320795 | 0.77 | ITGB1 (0.59) | ITGB1ITGAVCTSBCTSSCTSK | |
| SCHEMBL4627521 | 0.77 | ITGB1 (0.59) | ITGB1ITGAVCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008138592-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008125215-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-10-23 | — | — | WO | disclosed |