SCHEMBL4747309

SCHEMBL4747309

O=C1CSC(c2ccc(F)cc2)N1c1ccc(Oc2ccc(Cl)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 7/20 0.72
KMT2A Q03164 3/20 0.72
GFER P55789 2/20 0.72
MEN1 O00255 1/20 0.72
CA1 P00915 2/20 0.60
CA2 P00918 2/20 0.60
CA9 Q16790 2/20 0.60
PTGS2 P35354 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4743912 0.89 KMT2A (0.58) HTR7KMT2AGFERMEN1CA1
SCHEMBL4747357 0.88 PTGS2 (0.61) HTR7KMT2AGFERMEN1CA1
SCHEMBL4745920 0.88 CA1 (0.60) HTR7KMT2AGFERMEN1CA1
SCHEMBL4747947 0.88 GFER (0.72) HTR7KMT2AGFERMEN1CA1
SCHEMBL4743532 0.88 GFER (0.70) HTR7KMT2AGFERMEN1CA1
SCHEMBL4744309 0.87 CA1 (0.57) HTR7KMT2AGFERMEN1CA1
SCHEMBL4747362 0.87 CA1 (0.57) HTR7KMT2AGFERMEN1CA1
SCHEMBL4743497 0.87 KMT2A (0.56) HTR7KMT2AGFERMEN1CA1
SCHEMBL4743528 0.86 KMT2A (0.74) HTR7KMT2AGFERMEN1CA1
SCHEMBL4743525 0.85 CA1 (0.56) HTR7KMT2AGFERMEN1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008112674-A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY IRM LLC (BM) 2008-09-18 WO claimed
WO-2008112674-A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY IRM LLC (BM) 2008-09-18 WO disclosed
WO-2008112674-A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY IRM LLC (BM) 2008-09-18 WO disclosed