Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 9/20 | 0.53 |
| ▸ | PPARG | P37231 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748452 | 0.88 | FFAR1 (0.46) | FFAR1PPARAPPARGNPC1RAB9A | |
| SCHEMBL4788306 | 0.87 | FFAR1 (0.53) | FFAR1PPARAPPARGNPC1RAB9A | |
| SCHEMBL4747041 | 0.87 | FFAR1 (0.72) | FFAR1PPARAPPARGCYSLTR1PTGER4 | |
| SCHEMBL4746564 | 0.85 | PPARA (0.64) | FFAR1PPARAPPARGCYSLTR1 | |
| SCHEMBL4747337 | 0.84 | FFAR1 (0.53) | FFAR1PPARAPPARGPPARD | |
| SCHEMBL4748563 | 0.81 | PPARG (0.49) | FFAR1PPARAPPARGNPC1RAB9A | |
| SCHEMBL15762228 | 0.79 | HDAC1 (0.50) | PPARAPPARG | |
| SCHEMBL260484 | 0.76 | MAOB (0.58) | FFAR1NPC1RAB9APTGER4 | |
| SCHEMBL4787746 | 0.75 | NPC1 (0.43) | FFAR1PPARAPPARGNPC1RAB9A | |
| SCHEMBL4744018 | 0.75 | CD274 (0.51) | FFAR1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |