Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747663 | 0.87 | FFAR1 (0.63) | PPARGPPARAFFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9261947 | 0.84 | PPARG (0.49) | PPARGPPARAFFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4788306 | 0.81 | FFAR1 (0.53) | PPARGPPARAFFAR1SMN1; SMN2NPC1 | |
| SCHEMBL4747385 | 0.81 | FFAR1 (0.56) | PPARGPPARAFFAR1NPC1RAB9A | |
| SCHEMBL4747685 | 0.75 | FFAR1 (0.52) | PPARGPPARAFFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9520727 | 0.75 | PPARG (0.43) | PPARGPPARA | |
| SCHEMBL4748219 | 0.74 | MAOA (0.56) | PPARGPPARAFFAR1NPC1RAB9A | |
| SCHEMBL9178901 | 0.74 | MAOA (0.58) | PPARGPPARAFFAR1LMNANPC1 | |
| SCHEMBL14128011 | 0.74 | MAOB (0.61) | FFAR1ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL260403 | 0.74 | MAOB (0.61) | FFAR1ALDH1A1SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |