Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957 | 0.80 | CYP2A6 (0.32) | ALDH1A1MAPTCYP1A2CYP2A6CYP3A4 | |
| SCHEMBL28068731 | 0.78 | KDM4E (0.31) | ALDH1A1CYP1A2CYP2A6CYP3A4 | |
| Hydrochloric Acid SCHEMBL28618702 | 0.78 | KDM4E (0.33) | ALDH1A1MAPTCYP1A2CYP2A6CYP3A4 | |
| SCHEMBL8606886 | 0.71 | ALDH1A1 (0.48) | ALDH1A1GLAMAPTHPGDACHE | |
| SCHEMBL13156515 | 0.69 | ALDH1A1 (0.46) | ALDH1A1GLAMAPTHPGDACHE | |
| SCHEMBL13156571 | 0.69 | ALDH1A1 (0.46) | ALDH1A1GLAMAPTHPGDACHE | |
| SCHEMBL3141049 | 0.68 | ALDH1A1 (0.41) | ALDH1A1GLAMAPTHPGDACHE | |
| SCHEMBL2140440 | 0.65 | NQO2 (0.41) | ALDH1A1GLAMAPTHPGDACHE | |
| Anthracene SCHEMBL29352043 | 0.65 | CYP2A6 (0.64) | ALDH1A1GLAMAPTHPGDACHE | |
| Anthracene SCHEMBL7703 | 0.65 | CYP2A6 (0.64) | ALDH1A1GLAMAPTHPGDACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130515-A1 | ANTI-CANCER AGENTS, COMPOSITIONS AND METHODS OF TREATING CANCERS | ACB, LLC (US) | 2008-10-30 | — | — | WO | disclosed |
| US-20080255175-A1 | Anti-cancer agents, compositions and methods of treating cancers | ACB, LLC | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255175-A1 | Anti-cancer agents, compositions and methods of treating cancers | HCCS, EPOR, RAD51 | ALDH1A1 2244/4885GLA 1357/4885MAPT 4702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.