Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 16/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748386 | 0.97 | CD274 (0.53) | CD274PPARGPPARAPOLBPDCD1 | |
| SCHEMBL4748382 | 0.97 | CD274 (0.53) | CD274PPARGPPARAPOLBPDCD1 | |
| SCHEMBL4745017 | 0.91 | CD274 (0.62) | CD274PPARAPOLBPDCD1MEN1 | |
| SCHEMBL4746750 | 0.91 | CD274 (0.50) | CD274PPARGPPARAPOLBPDCD1 | |
| SCHEMBL4746755 | 0.91 | CD274 (0.50) | CD274PPARGPPARAPOLBPDCD1 | |
| SCHEMBL4744385 | 0.91 | CD274 (0.54) | CD274PPARGPPARAPDCD1 | |
| SCHEMBL4744265 | 0.89 | CD274 (0.59) | CD274PPARGPPARAPOLBPDCD1 | |
| SCHEMBL4744260 | 0.89 | CD274 (0.59) | CD274PPARGPPARAPOLBPDCD1 | |
| SCHEMBL4748001 | 0.88 | CD274 (0.50) | CD274PPARGPPARAPDCD1SPHK1 | |
| SCHEMBL4748002 | 0.88 | CD274 (0.50) | CD274PPARGPPARAPDCD1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |