Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.61 |
| ▸ | CA2 | P00918 | 8/20 | 0.61 |
| ▸ | CA9 | Q16790 | 8/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745893 | 0.92 | CA1 (0.58) | CA1CA2CA9HTR7GFER | |
| SCHEMBL4747311 | 0.89 | CA1 (0.54) | CA1CA2CA9HTR7GFER | |
| SCHEMBL4743965 | 0.87 | KMT2A (0.56) | CA1CA2CA9HTR7GFER | |
| SCHEMBL4747991 | 0.87 | CA1 (0.53) | CA1CA2CA9HTR7GFER | |
| SCHEMBL4743936 | 0.87 | CA1 (0.52) | CA1CA2CA9HTR7GFER | |
| SCHEMBL4743511 | 0.87 | KMT2A (0.55) | CA1CA2CA9HTR7GFER | |
| SCHEMBL4743953 | 0.85 | GFER (0.60) | CA1CA2CA9HTR7GFER | |
| SCHEMBL4747356 | 0.82 | HTR7 (0.51) | CA1CA2CA9HTR7GFER | |
| SCHEMBL4743942 | 0.82 | HTR7 (0.59) | CA1CA2CA9HTR7GFER | |
| SCHEMBL4744293 | 0.82 | GFER (0.56) | CA1CA2CA9HTR7GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | claimed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |