Streptozosin

Streptozosin

SCHEMBL4748

CN(N=O)C(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
KDM4E B2RXH2 1/20 1.00
CYP2D6 P10635 1/20 1.00
CYP2C19 P33261 1/20 1.00
HK2 P52789 5/20 0.45
HK1 P19367 4/20 0.45
MAPK1 P28482 2/20 0.42
PYGB P11216 6/20 0.39
GAA P10253 1/20 0.39
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Streptozosin SCHEMBL444089 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Streptozosin SCHEMBL18402590 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Streptozosin SCHEMBL13840968 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Streptozosin SCHEMBL17327962 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Streptozosin SCHEMBL15012795 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Streptozosin SCHEMBL10201155 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Streptozosin SCHEMBL17328035 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Streptozosin SCHEMBL10262780 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Streptozosin SCHEMBL18402588 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Streptozosin SCHEMBL444088 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 146332 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748859-A2 CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF The Regents of the University of California (US) 2026-05-27 EP claimed
CN-122075693-A Application of transcription factor CUX1 in preparation of product for preventing and treating diabetic foot ulcer 2026-05-26 CN claimed
CN-116209439-B Cereblon protein modulators Saint Jude Children's Research Hospital Ltd. (US) 2026-05-26 CN claimed
CN-122074448-A Progressive pathological animal model for drug evaluation and construction method thereof 2026-05-26 CN claimed
CN-122074048-A Methods of treating cancer 诺华股份有限公司 2026-05-22 CN claimed
WO-2026107377-A1 PHARMACOLOGICAL RE-ACTIVATION OF MUTANT PVHL KARANICOLAS JOHN (US) 2026-05-21 WO claimed
US-20260139071-A1 Subcutaneous Formulations Of Anti-CD38 Antibodies And Their Uses JANSSEN BIOTECH INC (US) 2026-05-21 US claimed
US-20260137794-A1 LIGAND-DRUG CONJUGATE AND USE THEREOF SYSTIMMUNE INC (US) 2026-05-21 US claimed
US-20260137650-A1 MODULATORS OF RAR RELATED ORPHAN RECEPTORS (RORs) 11949098 CANADA INC (CA) 2026-05-21 US claimed
WO-2026105121-A1 ANTICANCER FORMULATIONS AND USES THEREOF INTRAGEL THERAPEUTICS LTD. (IL) 2026-05-21 WO claimed
WO-1991014445-A1 HETEROVESICULAR LIPOSOMES RESEARCH DEVELOPMENT FOUNDATION (US) 1991-10-03 WO claimed
EP-0416286-A1 Sulfonylhydrazines and their use as antineoplastic agents and as antitrypanosomal agents YALE UNIVERSITY (US) 1991-03-13 EP claimed
US-4978332-A Reduced effect on cells distant from the site MATRIX PHARMACEUTICAL, INC. (US) 1990-12-18 US claimed
EP-0335966-A4 VASOCONSTRICTIVE SUBSTANCES IN COMBINATION WITH CYTOTOXIC AGENTS. MATRIX PHARMA INC (US) 1990-02-20 EP claimed
EP-0335966-A1 VASOCONSTRICTIVE SUBSTANCES IN COMBINATION WITH CYTOTOXIC AGENTS MATRIX PHARMACEUTICALS, INC. (US) 1989-10-11 EP claimed
WO-1989002734-A1 VASOCONSTRICTIVE SUBSTANCES IN COMBINATION WITH CYTOTOXIC AGENTS MATRIX PHARMACEUTICALS, INC. (US) 1989-04-06 WO claimed
EP-0222425-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-05-20 EP claimed
EP-0218300-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-04-15 EP claimed
EP-0110955-A1 BRAIN-SPECIFIC DRUG DELIVERY. UNIV FLORIDA (US) 1984-06-20 EP claimed
WO-1983003968-A1 BRAIN-SPECIFIC DRUG DELIVERY UNIVERSITY OF FLORIDA (US) 1983-11-24 WO claimed