Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.60 |
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383003 | 0.86 | PPARA (0.63) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL4744872 | 0.84 | PPARA (0.64) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL4748231 | 0.84 | PPARA (0.64) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL6204165 | 0.80 | PPARA (0.78) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL4031030 | 0.79 | PPARA (0.74) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL12442798 | 0.78 | PPARA (0.64) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL4031035 | 0.78 | PPARA (0.65) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL4025622 | 0.77 | PPARA (0.59) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL4031028 | 0.77 | PPARA (0.69) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL4025632 | 0.77 | PPARA (0.61) | PPARAPPARGPPARDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |