Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.64 |
| ▸ | PPARG | P37231 | 8/20 | 0.55 |
| ▸ | PPARD | Q03181 | 3/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383003 | 0.86 | PPARA (0.63) | PPARAPPARGPPARDFFAR1MAPT | |
| SCHEMBL4748231 | 0.84 | PPARA (0.64) | PPARAPPARGPPARDFFAR1MAPT | |
| SCHEMBL4031028 | 0.84 | PPARA (0.69) | PPARAPPARGPPARDFFAR1MAPT | |
| SCHEMBL4748145 | 0.84 | PPARA (0.60) | PPARAPPARGPPARDFFAR1MAPT | |
| SCHEMBL4025236 | 0.82 | PPARA (0.64) | PPARAPPARGPPARDFFAR1MAPT | |
| SCHEMBL4025622 | 0.82 | PPARA (0.59) | PPARAPPARGPPARDFFAR1MAPT | |
| SCHEMBL4031030 | 0.82 | PPARA (0.74) | PPARAPPARGPPARDFFAR1MAPT | |
| SCHEMBL5228001 | 0.82 | ALDH1A1 (0.52) | PPARAPPARGPPARDMAPTKDM4E | |
| SCHEMBL4746637 | 0.81 | FFAR1 (0.77) | PPARAPPARGPPARDFFAR1MAPT | |
| SCHEMBL6203331 | 0.81 | PPARA (0.65) | PPARAPPARGPPARDFFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |