Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 10/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8230137 | 0.82 | PIK3CG (0.48) | PIK3CGCYP1A2CYP11B1CYP11B2HTR6 | |
| SCHEMBL8231088 | 0.81 | PIK3CG (0.49) | PIK3CGCYP1A2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL2026420 | 0.80 | PIK3CG (0.66) | PIK3CGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2020904 | 0.80 | PIK3CG (0.66) | PIK3CGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8270165 | 0.80 | PIK3CG (0.66) | PIK3CGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4818333 | 0.79 | PIK3CG (0.45) | PIK3CGCYP1A2CYP11B1CYP11B2HTR6 | |
| SCHEMBL8237567 | 0.78 | PIK3CG (0.49) | PIK3CGCYP1A2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL4748031 | 0.78 | PIK3CG (0.41) | PIK3CGCYP11B2 | |
| SCHEMBL4328277 | 0.78 | PIK3CG (0.50) | PIK3CGCYP1A2CYP3A4CYP2C9CYP11B1 | |
| Isopropyl Alcohol SCHEMBL4983070 | 0.78 | PIK3CG (0.49) | PIK3CGCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130853-A1 | HYDRAZIDES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS - 681 | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | claimed |
| WO-2008130853-A1 | HYDRAZIDES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS - 681 | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | disclosed |