SCHEMBL474855

SCHEMBL474855

C=C(CCCC(CCCCCCCCCCCCC)N(CCCC)CCCC)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.39
FFAR4 Q5NUL3 1/20 0.39
GPR84 Q9NQS5 9/20 0.39
PPARD Q03181 3/20 0.38
MAPT P10636 1/20 0.38
LCK P06239 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
THRB P10828 1/20 0.37
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
PGGT1B P53609 1/20 0.37
ACE2 Q9BYF1 1/20 0.36
PPARG P37231 2/20 0.35
PPARA Q07869 2/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
SLC22A8 Q8TCC7 1/20 0.35
TLR2 O60603 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14054198 0.80 FFAR1 (0.46) FFAR1FFAR4GPR84PPARDMAPT
SCHEMBL14053915 0.80 FFAR1 (0.46) FFAR1FFAR4GPR84PPARDMAPT
SCHEMBL8051610 0.80 FFAR1 (0.46) FFAR1FFAR4GPR84PPARDMAPT
SCHEMBL867496 0.79 ACE2 (0.58) FFAR1FFAR4GPR84PPARDMAPT
SCHEMBL9327540 0.79 FFAR1 (0.62) FFAR1FFAR4GPR84MAPTACE2
SCHEMBL14054099 0.79 FFAR1 (0.44) FFAR1FFAR4GPR84PPARDMAPT
SCHEMBL14055316 0.79 FFAR1 (0.44) FFAR1FFAR4GPR84PPARDMAPT
SCHEMBL14053985 0.79 ACE2 (0.58) FFAR1FFAR4GPR84PPARDMAPT
SCHEMBL14053617 0.78 CA2 (0.47) FFAR1FFAR4GPR84PPARDMAPT
SCHEMBL14054360 0.78 FFAR1 (0.43) FFAR1FFAR4GPR84PPARDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2008506794-A 2008-03-06 JP claimed
US-20070213237-A1 USE OF GRAFT POLYMERS ROHMAX ADDITIVES GMBH (DE) 2007-09-13 US claimed
EP-1771532-A1 USE OF GRAFT POLYMERS Rohmax Additives GmbH (DE) 2007-04-11 EP claimed
WO-2006007934-A1 USE OF GRAFT POLYMERS ROHMAX ADDITIVES GMBH (DE) 2006-01-26 WO claimed
EP-1753847-B1 LUBRICATING GREASE HAVING A HIGH WATER-RESISTANCE EVONIK OIL ADDITIVES GMBH (DE) 2018-05-23 EP disclosed
EP-2686352-B1 COPOLYMERS COMPRISING ESTER GROUPS AND USE THEREOF IN LUBRICANTS EVONIK OIL ADDITIVES GMBH (DE) 2018-04-04 EP disclosed
EP-1235870-B1 BLOCK COPOLYMERS AND METHOD FOR THE PRODUCTION AND UTILIZATION THEREOF EVONIK OIL ADDITIVES GMBH (DE) 2017-05-24 EP disclosed
EP-2411426-B1 (METH)ACRYLATE POLYMERS AND THE USE THEREOF AS POLYMER-BOUND UV INITIATORS OR ADDITIVE TO UV-CURABLE RESINS EVONIK ROEHM GMBH (DE) 2016-08-17 EP disclosed
US-9175242-B2 Fluid having improved lubricity properties EVONIK ROHMAX ADDITIVES GMBH (DE) 2015-11-03 US disclosed
US-20140206823-A1 METHOD FOR REDUCING THE HALOGEN CONTENT OF A POLYMER EVONIK OIL ADDITIVES GMBH (DE) 2014-07-24 US disclosed
US-8785358-B2 Process for producing lubricating grease EVONIK ROHMAX ADDITIVES GMBH (DE) 2014-07-22 US disclosed
US-8754018-B2 Use of polyalkyl (meth)acrylates in lubricating oil compositions EVONIK ROHMAX ADDITIVES GMBH (DE) 2014-06-17 US disclosed
WO-2005108531-A2 USE OF POLYALKYL(METH)ACRYLATES IN LUBRICATING OIL COMPOSITIONS ROHMAX ADDITIVES GMBH (DE) 2005-11-17 WO disclosed
WO-2005108532-A1 LUBRICATING GREASE HAVING A HIGH WATER-RESISTANCE ROHMAX ADDITIVES GMBH (DE) 2005-11-17 WO disclosed
US-20050245406-A1 excellent consistency and great homogeneity; dispersion of thickener, lubricant, and structure improver is copolymer of a C6-C30 alkyl (meth)acrylate ROHMAX ADDITIVES GMBH (DE) 2005-11-03 US disclosed
US-20050148749-A1 Copolymers as dewaxing additives ROHMAX ADDITIVES GMBH (DE) 2005-07-07 US disclosed
WO-2004087850-A1 LUBRICATING OIL COMPOSITION WITH GOOD FRICTIONAL PROPERTIES ROHMAX ADDITIVES GMBH (DE) 2004-10-14 WO disclosed
EP-1453872-A1 COPOLYMERS AS DEWAXING ADDITIVES Rohmax Additives GmbH (DE) 2004-09-08 EP disclosed
EP-1240219-B1 COPOLYMERS WHICH CAN BE OBTAINED USING ATRP METHODS, AND METHOD FOR PRODUCING AND USING THE SAME ROHMAX ADDITIVES GMBH (DE) 2004-08-25 EP disclosed
WO-2003074578-A1 COPOLYMERS AS DEWAXING ADDITIVES ROHMAX ADDITIVES GMBH (DE) 2003-09-12 WO disclosed