Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.60 |
| ▸ | PPARA | Q07869 | 4/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748030 | 0.89 | PPARG (0.57) | PPARGPPARAFFAR1PPARDS1PR1 | |
| SCHEMBL4747337 | 0.88 | FFAR1 (0.53) | PPARGPPARAFFAR1PPARDSPHK2 | |
| SCHEMBL4748452 | 0.85 | FFAR1 (0.46) | PPARGPPARAFFAR1HRH3 | |
| SCHEMBL4748088 | 0.84 | FFAR1 (0.59) | PPARGPPARAFFAR1PPARDHRH3 | |
| SCHEMBL4744208 | 0.83 | PPARG (0.59) | PPARGPPARAFFAR1PPARDHRH3 | |
| SCHEMBL4905721 | 0.79 | PPARG (0.49) | PPARGPPARAS1PR1S1PR3PTPN1 | |
| SCHEMBL5901540 | 0.79 | PPARG (0.46) | PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL4746266 | 0.77 | PPARG (0.53) | PPARGPPARAFFAR1S1PR1HRH3 | |
| SCHEMBL4744017 | 0.77 | PPARG (0.53) | PPARGPPARAFFAR1S1PR1HRH3 | |
| SCHEMBL4746718 | 0.77 | FFAR1 (0.50) | PPARGPPARAFFAR1PPARDSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |