Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.59 |
| ▸ | PPARA | Q07869 | 6/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261947 | 0.89 | PPARG (0.49) | PPARGPPARAPTPN1FFAR1PPARD | |
| SCHEMBL4747685 | 0.85 | FFAR1 (0.52) | PPARGPPARAHRH3FFAR1 | |
| SCHEMBL4748030 | 0.83 | PPARG (0.57) | PPARGPPARAHRH3PTPN1FFAR1 | |
| SCHEMBL4748565 | 0.83 | PPARG (0.60) | PPARGPPARAHRH3PTPN1FFAR1 | |
| SCHEMBL4744060 | 0.78 | PPARA (0.62) | PPARGPPARAPTPN1PPARD | |
| SCHEMBL6958646 | 0.77 | PPARG (0.42) | PPARGPPARAHRH3FFAR1 | |
| SCHEMBL4788097 | 0.76 | PPARA (0.56) | PPARGPPARAFFAR1 | |
| SCHEMBL6956424 | 0.76 | PPARG (0.40) | PPARGPPARAHRH3FFAR1 | |
| SCHEMBL21331781 | 0.75 | ALDH1A1 (0.53) | PPARGPPARAPTPN1PPARDCHRNB2 | |
| SCHEMBL9261466 | 0.75 | PPARG (0.47) | PPARGPPARAPTPN1FFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |