Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.69 |
| ▸ | CA2 | P00918 | 4/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240962 | 0.88 | MAPT (0.59) | CA1CA2FFAR1FFAR4HIF1A | |
| SCHEMBL16213186 | 0.86 | CA1 (0.61) | CA1CA2FFAR1FFAR4HIF1A | |
| SCHEMBL4745601 | 0.84 | CA1 (0.71) | CA1CA2HIF1ANPC1RAB9A | |
| SCHEMBL11253864 | 0.84 | FFAR1 (0.68) | CA1CA2FFAR1FFAR4HIF1A | |
| SCHEMBL8755066 | 0.83 | CA1 (0.69) | CA1CA2FFAR1HIF1ANPC1 | |
| SCHEMBL16211427 | 0.82 | CA1 (0.75) | CA1CA2HIF1ANPC1RAB9A | |
| SCHEMBL18415526 | 0.82 | CA1 (1.00) | CA1CA2FFAR1FFAR4HIF1A | |
| SCHEMBL13934091 | 0.80 | CA1 (0.87) | CA1CA2HIF1ANPC1RAB9A | |
| SCHEMBL28218792 | 0.79 | HIF1A (0.72) | CA1CA2FFAR1HIF1AMAPT | |
| SCHEMBL15761753 | 0.78 | HIF1A (0.85) | CA1CA2HIF1ARAB9ASENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121570-A1 | COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2008-10-09 | — | — | WO | disclosed |