Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.81 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10904297 | 0.90 | ALOX5 (1.00) | ALOX5MEN1KMT2APOLBNPC1 | |
| SCHEMBL17993344 | 0.83 | HDAC2 (0.61) | ALOX5MEN1KMT2APOLBLMNA | |
| SCHEMBL14407440 | 0.83 | PTPN1 (0.58) | ALOX5MEN1KMT2APOLBLMNA | |
| SCHEMBL4746209 | 0.81 | MEN1 (0.60) | ALOX5MEN1KMT2APOLBNPC1 | |
| SCHEMBL299879 | 0.81 | KMT2A (0.88) | ALOX5MEN1KMT2APOLBNPC1 | |
| SCHEMBL30868371 | 0.81 | KMT2A (0.88) | ALOX5MEN1KMT2APOLBNPC1 | |
| SCHEMBL29951893 | 0.81 | ALOX5 (0.76) | ALOX5MEN1KMT2APOLBNPC1 | |
| SCHEMBL1120804 | 0.79 | MAPK1 (0.55) | ALOX5POLBNPC1RAB9AMAPT | |
| SCHEMBL3160310 | 0.79 | MEN1 (0.87) | ALOX5MEN1KMT2APOLBNPC1 | |
| SCHEMBL11729838 | 0.78 | ALOX5 (0.77) | ALOX5MEN1KMT2APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |