Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.58 |
| ▸ | ANPEP | P15144 | 3/20 | 0.44 |
| ▸ | KDM1A | O60341 | 4/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11185918 | 0.84 | CDK8 (0.53) | HTR2AANPEPKDM1ANOS3NOS2 | |
| SCHEMBL31373438 | 0.81 | — | — | |
| SCHEMBL31373436 | 0.81 | — | — | |
| SCHEMBL2463276 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL19926846 | 0.79 | KDM1A (0.57) | HTR2AANPEPKDM1AHRH1HTR2C | |
| Hydrochloric Acid SCHEMBL22635715 | 0.77 | HTR2A (0.54) | HTR2AANPEPKDM1AHRH1HTR2C | |
| SCHEMBL24399522 | 0.77 | S100A4 (0.52) | HTR2AANPEPACHE | |
| SCHEMBL20402534 | 0.77 | PLAU (0.54) | HTR2ANOS3NOS2ACHE | |
| SCHEMBL14870745 | 0.76 | HTR2A (0.55) | HTR2ANOS3NOS2HRH1ACHE | |
| SCHEMBL29439854 | 0.76 | HTR2A (0.55) | HTR2ANOS3NOS2HRH1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52142054-A | — | — | None | — | — | JP | disclosed |
| JP-52142054-A | — | — | None | — | — | JP | disclosed |
| WO-2008123821-A1 | 4, 5-DIHYDRO-LH-IMIDAZOL-2-AMINE DERIVATIVES FOR USE IN THE TREATMENT OF RESPIRATORY, CARDIOVASCULAR, NEUROLOGICAL OR GASTROINTESTINAL DISORDERS | ALBIREO AB (SE) | 2008-10-16 | — | — | WO | disclosed |
| JP-S52142054-A | 10-AMINO-9,10-DIHYROPHENANTHRENE DERIVATIVES AND THEIR PREPARATION | RES INST FOR PROD DEV | 1977-11-26 | — | — | JP | disclosed |
| JP-S52142054-A | 10-AMINO-9,10-DIHYROPHENANTHRENE DERIVATIVES AND THEIR PREPARATION | RES INST FOR PROD DEV | 1977-11-26 | — | — | JP | disclosed |