Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475760 | 0.89 | KDM4E (0.56) | L3MBTL1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL4751276 | 0.89 | CA12 (0.38) | L3MBTL1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL16223742 | 0.84 | KMT2A (0.38) | L3MBTL1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL165562 | 0.84 | KDM4E (0.51) | L3MBTL1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL7868931 | 0.84 | KDM4E (0.51) | L3MBTL1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL15276344 | 0.81 | CA12 (0.39) | L3MBTL1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL17747120 | 0.81 | CA1 (0.54) | L3MBTL1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL12180307 | 0.81 | L3MBTL1 (0.51) | L3MBTL1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL3446204 | 0.81 | CA12 (0.58) | L3MBTL1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL3595760 | 0.80 | L3MBTL1 (0.51) | L3MBTL1KMT2ALMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135488-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008135488-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2008-11-13 | — | — | WO | disclosed |