Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.69 |
| ▸ | CFD | P00746 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.59 |
| ▸ | MASP2 | O00187 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462332 | 0.92 | KDM4E (0.71) | DHODHCFDKMT2AMEN1KDM4E | |
| SCHEMBL31580808 | 0.92 | KDM4E (0.71) | DHODHCFDKMT2AMEN1KDM4E | |
| SCHEMBL16127718 | 0.90 | CA12 (0.60) | DHODHCFDKMT2AMEN1KDM4E | |
| SCHEMBL5605545 | 0.89 | KDM4E (0.64) | DHODHCFDKMT2AMEN1KDM4E | |
| SCHEMBL8686791 | 0.88 | ALDH1A1 (0.70) | DHODHCFDKMT2AMEN1KDM4E | |
| SCHEMBL13936398 | 0.86 | DHODH (0.64) | DHODHCFDKMT2AMEN1KDM4E | |
| SCHEMBL211260 | 0.86 | KMT2A (0.61) | DHODHCFDKMT2AMEN1KDM4E | |
| SCHEMBL299823 | 0.86 | GRIK1 (0.69) | DHODHCFDKMT2AMEN1KDM4E | |
| SCHEMBL6434424 | 0.86 | KDM4E (0.74) | CFDKMT2AMEN1KDM4ENPC1 | |
| SCHEMBL6326283 | 0.84 | KMT2A (0.62) | DHODHCFDKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |
| US-4786706-A | FIBERS, FILMS AND MOLDINGS | BASF AKTIENGESELLSCHAFT (DE) | 1988-11-22 | — | — | US | disclosed |
| US-4762907-A | Wholly aromatic polyester carbamides and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| US-4473681-A | Polyester urea capable of forming an anisotropic melt phase | CELANESE CORPORATION (US) | 1984-09-25 | — | — | US | disclosed |